Guiding Principles

Guiding principlesAs a new group we need to be strategic. In the first few years of Cadence we will concentrate on 'augmentation' or add-on studies, where everyone still receives standard care, but patients are randomized to a candidate treatment or placebo.

Also, we will concentrate on interventions that are safe and more readily acceptable to people with early psychosis.

We will undertake high quality ethical research, based on respect for participants and clinicians. We are keen for people with psychosis (and their families) to understand the importance of clinical trials, and help us develop better treatments in the decades ahead.

We want to do studies that are as 'pragmatic' as possible i.e. that accept a wide range of participants, that do not disrupt ordinary clinical care, and that concentrate on clinically meaningful outcomes.

What does "Cadence" mean?

The name “Cadence” has many musical connotations including rhythm, harmony and balance. It also pays tribute to John Cade. In this video Professor McGrath explains why he chose the name Cadence.


Partnership with citizen scientists

In this video Associate Professor James Scott explains how the Cadence team wants to work in partnership with people with early psychosis as “citizen scientists”.